Jack Black and Paul Rudd lead the ensemble cast of Anaconda , portraying members of a friend group experiencing mid-life crises. The cast also features Daniela Melchior, Steve Zahn, Thandiwe Newton, Selton Mello, Ione Skye, and Rui Ricardo Diaz

Best friends Griff and Doug have always dreamed of remaking their all-time favorite movie "Anaconda." When a midlife crisis pushes them to finally go for it, they assemble a crew and head deep into the jungles of the Amazon to start filming. However, life soon imitates art when a gigantic anaconda with a thirst for blood starts hunting them down.